China's top tier cities may elevate themselves from regional centers to future global metropolises, with advantages in sectors𒉰 such 🍸as smart cities and artificial intelligence.

International investors from global giants like Boeing, Merck and Siemens share🦩d this view at the Annual Investment Conference in South China's Guangzhou on Wednesday.

The conference is a major event aimed at promoting the city to potential investors and listening to their comments on its business environment. Over 1,800 enterprises from around the w♉orld attended the conference.

Many inve꧃stors stated that China is no💃w more than just a large market for them.

This year China is celebrating the 4🗹0th anniversary ✱of its reform and opening-up.

Merck, a world lead🌟ing company in health care, life science and performance materials, has been operating in China for over 80 years. As well as its existing research and development centers and labs in Beijing and Shanghai, the co👍mpany established a new China Innovation Center in Shanghai in February.

"The opening-up of China has made a great differencജe to our business and it allowed us to advance business sectors liquid crystal and pigments," said Allan Gabor, manag🌼ing director of Merck China.

"When Merck looks atꦦ China, we🎀 see China as much more than a large business market, we see it actually as an enabler of our global strategy," Gabor added.

Similarly, John Bruns, vice president of Boeing Internati😼onal, said China is now "a source of innovation" from the company's perspective.

The American aviation giant will soon open its first finishing and deliver𓄧ing center for 737 planes outside the United States in East China near Shanghai, and recently signed an agreement with China Southern Airlines to initiate a 737 converted freight project in꧒ Guangzhou, and to include a local maintenance company in its 787 global care program.

Citieಌs like Beijing, Shanghai, Guangzhou and Shenzhen, and the Greater Bay Area of Guangdong, Hong Kong and Macao, are becoming the key players in investors' global strategies.

These cities have mature urban infrastructure, advanced industries and are renewing their focus on development to be in line wi♉th the information revolution and an international lifestyle.

Guangzhou, for example, is focusing on the new gene༒ration of information technology, artificial intelligence, bio-pharmaceuticals, as well as new energy and new materials.

The output of its new generation in꧋ternet technology and panel display ♓industries have both exceeded 100 billion yuan. It is also ambitious in becoming a smart city, by teaming up with global giants like Cisco and Siemens.

New York and London🐻 are ♕indisputably global cities now, but what will global cities of the future look like?

"A future global city should be leading in smart mobility and smart energy distribution and future technology like AI. I think Guangzhou i♑s on a very good way to that," said Jens Hildebrandt, chief representative o🉐f Delegation of German Industry and Commerce Guangzhou.

But investors🎐 also pointed out that Chinese cities still need to tackle a series of challenges before they become global cities, including IPR protection, environmental protection, further opening-up and continuous innovation, as well as self promotion.

These ar✨e also the a꧑reas where huge opportunities lie.

Three months ago, SHV Energy, the world's largest distributor of LPG energy solutions, signed an memorandum of understandi🐼ng with Guangdong province, to build a LPG terminal in the city's Nansha district.

"With the strong focus of the Chinese govဣernment to improve air quality and reduce emissions, you see a higher need for clean energy solutions." said Maarten Bijl, global v🅰ice president of the company.

He added that SHV is also innovating its business model and looking for cleaner energy solutions in which it can cooperate with the Chinese cities. "We're in discussion to see how 🧜we can work with the city of Guangzhou, and we can get hydrogen mobility 🥂solutions here, which is the next step."

Aside from the top tier cities, China as a whole is putting every effort to further open up. Earlier this month, the government pledged t✃o continue to streamline administration and delegate power to🐓 improve the business environment and further stimulate market vitality.